alpha smooth muscle Actin (ACTA2) Mouse Monoclonal Antibody [Clone ID: 1A4/asm-1]

Specifications

Product Data
Clone Name	1A4/asm-1
Applications	IHC
Recommend Dilution	Immunohistochemistry on Formalin Fixed Paraffin Embedded Sections: Use Actin antibody at 1/25-1/50 dilution in an ABC method for 30 minutes at room temperature. Recommended Positive Control: Leiomyoma colon.
Reactivity	Bovine, Chicken, Human, Mouse, Rabbit, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	N-terminal decapeptide of alpha-smooth muscle Actin
Specificity	This antibody is specific to alpha-smooth isoform of actin. It reacts with smooth muscle cells of vessels and different parenchymes. The antibody does not cross-react with beta and gamma-cytoplasmic, alpha-sarcomeric and alpha-myocardial actin isoforms. Cellular Localization: Cytoplasmic.
Formulation	State: Purified State: Liquid purified Ig fraction containing Sodium Azide as preservative
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	actin, alpha 2, smooth muscle, aorta
Database Link	Entrez Gene 59 Human UniProt ID P62736
Background	Smooth muscle actin is expressed in normal smooth muscle and in myoepithelial cells, and also in tumours derived from these cells. Actins are involved in maintaining the structure and integrity of a cell, as well as cell motility. They are highly conserved proteins and make up the majority of the contractile apparatus. To date, six different actin isoforms have been described.
Synonyms	ACTSA, ACTVS, Alpha-actin-2
Reference Data

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