Cd207 Rat Monoclonal Antibody [Clone ID: 923B7]
CAT#: DDX0373A546-100
Cd207 rat monoclonal antibody, clone 923B7
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CNY 6,281.00
货期*
4周
规格
Specifications
Product Data | |
Clone Name | 923B7 |
Applications | IF |
Recommend Dilution | DDX0373P-50 / DDX0373P-100 Purified: IHC, Flow cytometry. DDX0373A488-50 / DDX0373A488-100 Alexa-fluor®488: IF surface Flow cytometry. DDX0373A546-50 / DDX0373A546-100 Alexa-fluor®546: IF. DDX0373A647-50 / DDX0373A647-100 Alexa-fluor®647: Flow cytometry. DDX0373B-50 / DDX0373B-100 Biotin: Flow cytometry. Usage recommendation: *This monoclonal antibody may be used between 5-20 μg/ml. *Optimal dilution should be determined by each laboratory for each application. *Coupled antibody: to maintain RT before using. |
Reactivity | Human, Mouse, Rat |
Host | Rat |
Clonality | Monoclonal |
Immunogen | Human Langerin-transfected eukaryotic cells. |
Specificity | Human Langerin (extracellular epitope). Species cross-reactivity: Rat, Mouse. |
Formulation | Purified: 100 μg in 200μl / 50 μg in 100 μl Tris-NaCl pH 8. Coupled: 100 μg in 200μl / 50 μg in 100 μl PBS 50% glycerol. Label: Alexa Fluor 546 |
Concentration | lot specific |
Purification | Hyper-D ion exchange chromatography |
Conjugation | Alexa Fluor 546 |
Storage Condition | -20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing. |
Gene Name | CD207 antigen |
Database Link | |
Background | Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck’s granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 2002 J Immunol, 168 : 782-792) (Douillard P et al, 2005 J Invest Dermatol, 125: 983–994). |
Synonyms | CLEC4K, Dendritic Cell Marker |
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