DC SIGN (CD209) Mouse Monoclonal Antibody [Clone ID: 109H12.03]

CAT#: DDX0207P-100

DC SIGN (CD209) mouse monoclonal antibody, clone 109H12.03



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CNY 4,988.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name 109H12.03
Applications FC, IF, IHC
Recommend Dilution Surface Flow cytometry, IHC, IF
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Immunogen human DC-SIGN-transfected HeLa cells
Specificity Human DC-SIGN
Species cross-reactivity: L-SIGN, Mouse DC-SIGN.
Formulation Tris-NaCl pH 8
State: Purified
Concentration lot specific
Conjugation Unconjugated
Storage Condition Aliquot storage conditions -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing.
Gene Name CD209 molecule
Background DC-SIGN (“DC Specific, ICAM-3 Grabbing, Nonintegrin”)/CD209 and liver/lymph node-specific ICAM-3-grabbing nonintegrin (L-SIGN) (CD299/DC-SIGNR for DC-SIGN-related molecule; DC-SIGN2) are closely related genes that map to chromosome 19p13.3. Both genes encode a member of the C-type lectin family of type II transmembrane proteins. The two receptors are 77% identical at the amino acid level, have similar ligands. They are expressed in different tissues. Both receptors have been shown to interact with ICAM-3 DC-SIGN is a high affinity receptor for HIV gp120 (Soilleux EJ. 2003, Clinical Science 104, 437-; Dakappagari N., et al. 2006, The J Immunol, 176, 426; Geijtenbeeck T.B., et al. 2000, Cell, 100, 57 ; .Bashirova A. et al., 2001, J.Exp. Med., 193, 671 ; Canard B et al, Immunol Lett. 2011, 135(1-2):165-72 ; Rochereau N. et al, Vaccine 201; Kwan WH et al, PLoS Negl.Trop.Dis, 2:e311, 2008).
Synonyms DCSIGN1, DCSIGN, DC-SIGN1, CLEC4L, Dendritic Cell Marker
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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