Mps1 (TTK) Mouse Monoclonal Antibody [Clone ID: OTI13E9]

CAT#: CF811813

Carrier-free (BSA/glycerol-free) TTK mouse monoclonal antibody,clone OTI13E9

Formulation: Standard Carrier-Free



  View other "OTI13E9" antibodies (4)

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CNY 3,999.00


货期*
2周

规格
    • 100 ug

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Specifications

Product Data
Clone Name OTI13E9
Applications WB
Recommend Dilution WB 1:500
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 189-464 of human TTK (NP_003309) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 96.9 kDa
Gene Name TTK protein kinase
Background This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Synonyms CT96; ESK; MPH1; MPS1; MPS1L1; PYT
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Cell cycle, Oocyte meiosis, TGF-beta signaling pathway, Ubiquitin mediated proteolysis, Wnt signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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