PYGM Mouse Monoclonal Antibody [Clone ID: OTI5D1]

Specifications

Product Data
Clone Name	OTI5D1
Applications	IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:2000
Reactivity	Human, Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 698-842 of human PYGM (NP_005600) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	glycogen phosphorylase, muscle associated
Database Link	NP_005600 Entrez Gene 19309 MouseEntrez Gene 24701 RatEntrez Gene 5837 Human UniProt ID P11217
Background	This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Synonyms	glycogen; glycogen phosphorylase; glycogen storage disease type V; glycogen storage disease type V); McArdle syndrome; muscle; muscle (McArdle syndrome; myophosphorylase; phosphorylase
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Insulin signaling pathway, Starch and sucrose metabolism

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