ZIC3 Mouse Monoclonal Antibody [Clone ID: OTI1G7]

Specifications

Product Data
Clone Name	OTI1G7
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 242-467 of human ZIC3(NP_003404) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50.4 kDa
Gene Name	Zic family member 3
Database Link	NP_003404 Entrez Gene 22773 MouseEntrez Gene 7547 Human UniProt ID O60481
Background	This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. [provided by RefSeq, Jul 2008]
Synonyms	HTX; HTX1; VACTERLX; ZNF203
Reference Data
Protein Families	Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS

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