SENP1 Mouse Monoclonal Antibody [Clone ID: OTI1D7]

Specifications

Product Data
Clone Name	OTI1D7
Applications	FC, WB
Recommend Dilution	WB 1:1000, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 221-460 of human SENP1 (NP_055369) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	73.2 kDa
Gene Name	SUMO specific peptidase 1
Database Link	NP_055369 Entrez Gene 223870 MouseEntrez Gene 29843 Human UniProt ID Q9P0U3
Background	The covalent modification of proteins by the small ubiquitin (UBB; MIM 191339)-like protein SUMO (see SUMO1, MIM 601912) is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1 (Yamaguchi et al., 2005 [PubMed 15923632]). [supplied by OMIM]
Synonyms	SuPr-2
Reference Data
Protein Families	Druggable Genome, Protease

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