JNK2 (MAPK9) Mouse Monoclonal Antibody [Clone ID: OTI4D1]
CAT#: CF505910
Carrier-free (BSA/glycerol-free) MAPK9 mouse monoclonal antibody, clone OTI4D1 (formerly 4D1)
Formulation: Standard
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI4D1 |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:200~2000, IHC 1:150, IF 1:100 |
Reactivity | Human, Dog, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human MAPK9(NP_620707) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 43.9 kDa |
Gene Name | mitogen-activated protein kinase 9 |
Database Link | |
Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008] |
Synonyms | JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; p54a; p54aSAPK; PRKM9; SAPK; SAPK1a |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase |
Protein Pathways | Adipocytokine signaling pathway, Colorectal cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, GnRH signaling pathway, Insulin signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, Wnt signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA505910 | MAPK9 (JNK2) mouse monoclonal antibody, clone OTI4D1 (formerly 4D1) |
CNY 1,999.00 |
|
TA505910AM | MAPK9 mouse monoclonal antibody,clone 4D1, Biotinylated |
CNY 3,990.00 |
|
TA505910BM | MAPK9 mouse monoclonal antibody,clone 4D1, HRP conjugated |
CNY 3,990.00 |
|
TA505910S | MAPK9 (JNK2) mouse monoclonal antibody, clone OTI4D1 (formerly 4D1) |
CNY 800.00 |