FTCD Mouse Monoclonal Antibody [Clone ID: OTI8C2]

Specifications

Product Data
Clone Name	OTI8C2
Applications	IHC, WB
Recommend Dilution	WB 1:1000, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human FTCD(NP_006648) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	58.7 kDa
Gene Name	formimidoyltransferase cyclodeaminase
Database Link	NP_006648 Entrez Gene 10841 Human UniProt ID O95954
Background	The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.
Synonyms	LCHC1
Reference Data
Protein Pathways	Histidine metabolism, Metabolic pathways, One carbon pool by folate

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