LGALS3BP Mouse Monoclonal Antibody [Clone ID: OTI2B1]

Specifications

Product Data
Clone Name	OTI2B1
Applications	FC, WB
Recommend Dilution	WB 1:2000, FLOW 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human reocombinant protein fragmen corresponding to amino acids19-300 of human LGALS3BP(NP_005558) produced in E.coil.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	65.2 kDa
Gene Name	galectin 3 binding protein
Database Link	NP_005558 Entrez Gene 3959 Human UniProt ID Q08380
Background	The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq]
Synonyms	90K; BTBD17B; CyCAP; gp90; M2BP; MAC-2-BP; TANGO10B
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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