AKR1A1 Mouse Monoclonal Antibody [Clone ID: OTI2E7]

Specifications

Product Data
Clone Name	OTI2E7
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:50
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human AKR1A1 (NP_006057) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	36.6 kDa
Gene Name	aldo-keto reductase family 1 member A1
Database Link	NP_006057 Entrez Gene 58810 MouseEntrez Gene 78959 RatEntrez Gene 10327 Human UniProt ID P14550
Background	This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Alternative splicing of this gene results in two transcript variants encoding the same protein.
Synonyms	ALDR1; ALR; ARM; DD3; HEL-S-6
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways

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