BubR1 (BUB1B) Mouse Monoclonal Antibody [Clone ID: OTI11G2]
CAT#: CF500540
Carrier-free (BSA/glycerol-free) BUB1B mouse monoclonal antibody, clone OTI11G2 (formerly 11G2)
Formulation: Standard
View other "OTI11G2" antibodies (4)
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI11G2 |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:2000 IHC 1:50 IF 1:100 |
Reactivity | Human, Monkey |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full-length protein expressed in 293T cell transfected with human BUB1B expression vector |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 119.5 kDa |
Gene Name | BUB1 mitotic checkpoint serine/threonine kinase B |
Database Link | |
Background | This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome(APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. |
Synonyms | Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Stem cell - Pluripotency |
Protein Pathways | Cell cycle |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA500540 | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI11G2 (formerly 11G2) |
CNY 1,999.00 |
|
TA500540AM | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI11G2 (formerly 11G2), Biotinylated |
CNY 3,990.00 |
|
TA500540BM | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI11G2 (formerly 11G2), HRP conjugated |
CNY 3,990.00 |
|
TA500540S | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI11G2 (formerly 11G2) |
CNY 800.00 |