Desmoplakin (DSP) Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot: 1/1000. Immunofluorescence : 1/100. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Embedded Sections: 1/50 (ABC method) using Microwave method. Incubation time: 1 h at RT (extended with paraffin sections).
Reactivity	Bovine, Human
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Human Desmoplakin 1 (C-terminus of recombinant Human Desmoplakin 1).
Specificity	In Western blot analysis the antiserum reacts specifically with the Desmoplakin 1 polypeptide. The antiserum shows distinct punctate membrane staining of epithelia. Tested Reactivities on cultured cell lines: MCF-7, A-431, HaCaT, CaCo2.
Formulation	State: Serum State: Liquid stabilized antiserum
Conjugation	Unconjugated
Storage Condition	Store unditued at 2-8°C.
Gene Name	desmoplakin
Database Link	Entrez Gene 1832 Human UniProt ID P15924
Synonyms	DP, DSP, 250/210 kDa paraneoplastic pemphigus antigen
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Arrhythmogenic right ventricular cardiomyopathy (ARVC)

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