Desmoglein 2 (DSG2) Mouse Monoclonal Antibody [Clone ID: G96]

Specifications

Product Data
Clone Name	G96
Applications	ELISA, IHC, WB
Recommend Dilution	Western Blot. Immunohistochemistry on frozen sections: Ready-to-use; 1 h at RT; preincubation with 0.05 - 0.2% Triton X-100, for 5-10 min, depending on tissue type, is recommended. Immunohistochemistry on paraffin sections (enhanced when using the microwave method): Ready-to-use; overnight at 2-8°C. ELISA.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant peptide (220aa of 2nd and 3rd extracellular repeat domain)
Specificity	Antibody recognizes desmoglein 2 present in all epithelia and in tumors derived therefrom as well as in heart muscle and dendritic reticulum cells of lymphatic follicles. In basal epithelial cells desmoglein 2 expression is generally very low.
Formulation	State: Supernatant State: Liquid culture supernatant contains 0.09% NaN3
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	desmoglein 2
Database Link	Entrez Gene 1829 Human UniProt ID Q14126
Background	Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
Synonyms	DSG2, CDHF5,HDGC
Reference Data

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