Histone H1 Mouse Monoclonal Antibody [Clone ID: AE-4]

CAT#: BM465S

Histone H1 mouse monoclonal antibody, clone AE-4, Purified



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CNY 4,724.00


货期*
5周

规格
    • 100 ug

Cited in 7 publications.

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Specifications

Product Data
Clone Name AE-4
Applications ELISA, IF, IHC, IP, WB
Recommend Dilution ELISA. 
Western blotting
Immunoprecipitation. 
Immunofluorescence. 
Immunhistology on Frozen and Paraffin Sections: Acetone or PFA fixation is recommended for Frozen sections. Positive Control Tissue: Tonsil.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen A BALB/c mouse was immunized with Human leukemia biopsy cells.
The isolated splenocytes were fused with mouse myeloma cells.
Specificity AE-4 recognizes Histone H1 in the nuclei of animal and plant cells. It produces a speckled nuclear staining pattern in normal and malignant cells. Tonsil is the recommended positive control tissue.
Formulation PBS
State: Purified
State: Liquid purified IgG fraction
Preservative: 0.02% Sodium Azide
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C.
Background The histone proteins serve as a structural scaffold for the organisation of nuclear DNA into chromatin. In eucariotic cells there are 4 core histone proteins, H2A, H2B, H3 and H4 that asseble to form an octamer round which the DNA is wrapped in a sequence dependant manner. The resulting complex is known as a nucleosome and is the basic subunit of chromatin. Histone H1 acts as a linker and binds to each nucleosome, and by self affinity, links these nucleosomes together resulting in the 30 nm chromatin fiber.
Synonyms H1 Histone Family, H1F4, H1F5, Histone H1a, Histone H1b
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (7)

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