Iba1 (AIF1) Mouse Monoclonal Antibody [Clone ID: 1022-5]

Specifications

Product Data
Clone Name	1022-5
Applications	FC, IHC
Recommend Dilution	Has been described to work in FACS and Immunohistochemistry on Paraffin Sections.
Reactivity	Human, Porcine, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Human recombinant AIF-1. Epitope not further characterized.
Specificity	The antibody reacts with AIF-1.
Formulation	PBS, pH 7.2 Label: FITC State: Liquid purified IgG fraction Stabilizer: 10 mg/ml BSA Preservative: 0.09% Sodium Azide
Concentration	0.4 mg/ml
Purification	Affinity Chromatography
Conjugation	FITC
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	allograft inflammatory factor 1
Database Link	Entrez Gene 29427 RatEntrez Gene 199 Human UniProt ID P55008
Background	Allograft Inflammatory Factor-1 is a Ca2+-binding peptide produced by activated macrophages and microglial cells. It has been suggested that AIF-1 expression is associated with chronic inflammatory processes. AIF-1, like the Ca2+-binding peptides MRP8 and MRP14, is expressed by activated macrophages and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. The recently described apoptosis-inducing factor AIF is not related to AIF-1.
Synonyms	AIF-1, Protein G1, IBA1, Allograft inflammatory factor 1
Reference Data
Protein Families	Druggable Genome

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