Neutrophil Elastase (ELANE) Mouse Monoclonal Antibody [Clone ID: 39A]
CAT#: BM382
Neutrophil Elastase (ELANE) mouse monoclonal antibody, clone 39A, Purified
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CNY 6,116.00
货期*
4周
规格
Cited in 1 publication. |
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Specifications
Product Data | |
Clone Name | 39A |
Applications | ELISA, FC, FN |
Recommend Dilution | ELISA. Flow Cytometry. Functional Assays. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Elastase from Human Neutrophils. |
Specificity | This antibody is specific for Neutrophil Elastase. |
Formulation | PBS, pH 7.2 State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | elastase, neutrophil expressed |
Database Link | |
Background | Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Elastase is a serine protease which exhibits endopeptidase activity on many proteins, its principal substrate, however, is elastin and it is unique among proteases in its ability to hydrolyse native elastin. It is present in the pancreas, leukocytes and serum. Elastase consists of a single polypeptide chain with a molecular weight of 29.5kDa. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. Elastase 1 is not a pancreatic enzyme: clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A. |
Synonyms | ELANE, ELA2, Neutrophil elastase, Elastase-2, PMN elastase, Bone marrow serine protease, Medullasin, Human leukocyte elastase, HLE |
Reference Data |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Extracellular neutrophil traps in periodontitis.
,null,
Journal of periodontal research
,PubMed ID 19453857
[ELANE]
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