Neutrophil Elastase (ELANE) Mouse Monoclonal Antibody [Clone ID: 39A]

CAT#: BM382

Neutrophil Elastase (ELANE) mouse monoclonal antibody, clone 39A, Purified



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CNY 6,116.00


货期*
4周

规格
    • 200 ug

Cited in 1 publication.

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Specifications

Product Data
Clone Name 39A
Applications ELISA, FC, FN
Recommend Dilution ELISA.
Flow Cytometry.
Functional Assays.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Elastase from Human Neutrophils.
Specificity This antibody is specific for Neutrophil Elastase.
Formulation PBS, pH 7.2
State: Purified
State: Liquid purified IgG fraction
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name elastase, neutrophil expressed
Background Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Elastase is a serine protease which exhibits endopeptidase activity on many proteins, its principal substrate, however, is elastin and it is unique among proteases in its ability to hydrolyse native elastin. It is present in the pancreas, leukocytes and serum. Elastase consists of a single polypeptide chain with a molecular weight of 29.5kDa. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. Elastase 1 is not a pancreatic enzyme: clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.
Synonyms ELANE, ELA2, Neutrophil elastase, Elastase-2, PMN elastase, Bone marrow serine protease, Medullasin, Human leukocyte elastase, HLE
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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