Collagen I (COL1A1) Mouse Monoclonal Antibody [Clone ID: NFI/20]

CAT#: BM331

Collagen I (COL1A1) mouse monoclonal antibody, clone NFI/20, Purified



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CNY 4,587.00


货期*
4周

规格
    • 100 ug

Cited in 2 publications.

Product images

Specifications

Product Data
Clone Name NFI/20
Applications ELISA, IHC
Recommend Dilution ELISA: 1/500-1/2000.
Immunohistochemistry on Frozen Sections: 1/10-1/40.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human Collagen type I from placenta.
Specificity This antibody clone NFI/20 is specific for Human Collagen I and does not recognize Collagen types II, III and IV.
Formulation Buffer: 0.1M Sodium Chloride, 0.01M Sodium Phosphate, 0.01M Sodium Borate, with 1% Mannitol and 1% Dextran.
State: Purified
State: Lyophilized Ig fraction.
Reconstitution Method Restore with 1 ml of sterile distilled water.
Purification Ammonium Sulphate Precipitation and DEAE-Cellulose Chromatography.
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Gene Name collagen type I alpha 1
Background Collagen is located in the extracellular matrix of connective tissues. It is part of the interacting network of proteoglycans and proteins that provides a structural framework for both soft and calcified connective tissues. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon.
Mutations in the encoding gene are associated with osteogenesis imperfecta (Peng et al. 2012), Ehlers Danlos syndrome (Nuytinck et al. 2000) and idiopathic juvenile osteoporosis (Pocock et al. 1995). Defective processing of collagen I by lysyl hydroxylase has also been implicated in Ehlers Danlos syndrome (Ihme et al. 1984).
Synonyms COL1A1, COL1A2, Alpha-1 type I collagen, Alpha-2 type I collagen
Reference Data
Protein Families Druggable Genome
Protein Pathways ECM-receptor interaction, Focal adhesion
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)

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