Hepatitis B Surface Antigen / HBsAg (adw) Mouse Monoclonal Antibody [Clone ID: S26]

Specifications

Product Data
Clone Name	S26
Applications	ELISA, EM, IF, IHC, WB
Recommend Dilution	Suitable for use in Immunofluorescent and immunoperoxidase staining, Western blot, ELISA and Immuno electron microscopy.
Reactivity	Hepatitis B Virus
Host	Mouse
Clonality	Monoclonal
Immunogen	HBsAg from human sera pool.
Specificity	HBsAg pre-S2 antigen (a.a. 132-137) (adw nomenclature). Reference start codon was Pre-S1. Epitope recognition confirmed by competing with peptides.
Formulation	PBS, pH 7.4 without preservative. State: Azide Free State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing.
Background	Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
Synonyms	HBV surface antigen, Hepatitis B Virus
Reference Data

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