alpha 1 Fetoprotein (AFP) Mouse Monoclonal Antibody [Clone ID: 1301]

Specifications

Product Data
Clone Name	1301
Applications	ELISA, R
Recommend Dilution	For Enzyme conjugation, Radio-labeling or Solid Phase Immobilization. Suitable as detection antibody for Immunoassay.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified AFP from Cord Blood
Specificity	This antibody reacts with Human alpha Fetoprotein. No cross reactivity with Human albumin, CEA, Ferritin, hCG, PSA.
Formulation	PBS, pH 7.4, containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	alpha fetoprotein
Database Link	Entrez Gene 174 Human UniProt ID P02771
Background	Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries.
Synonyms	Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP
Reference Data

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