Serotonin Rat Monoclonal Antibody [Clone ID: YC5/45]

Specifications

Product Data
Clone Name	YC5/45
Applications	IF, IHC
Recommend Dilution	Immunofluorescence. Immunohistochemistry on Frozen Sections: Formaldehyde fixation is recommended (See Ref.1)
Reactivity	Guinea Pig, Human, Mouse, Rabbit, Rat, Xenopus
Host	Rat
Clonality	Monoclonal
Immunogen	Serotonin conjugated to Bovine Serum Albumin.
Specificity	This Serotonin Monoclonal antibody, clone YC5/45 recognizes Serotonin and does not cross react with 5-Hydroxyindolacetic Acid, GABA, noradrenaline, 5-Hydroxytryptophan, Carnosine or Melatonin. Serotonin appears widely conserved and Rat anti serotonin antibody, clone YC5/45 has been used successfully to demonstrate serotonin immunoreactiviy using immunohistochemistry in many diverse groups including primates (Vanoli et al. 2013), rodents (Hosoda et al. 1984), prototherian mammals, avians and reptiles (Adamson and Campbell 1988), teleosts (Takeda et al. 2014) through to invertebrates including hirudinids (Masuda-Nakagawa et al. 1990) and gastropods (Osborne and Dockray 1982).
Formulation	State: Supernatant State: Liquid Tissue Culture Supernatant Preservative: 0.01% Thiomersal
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Serotonin (also known as 5-hydroxytryptamine or 5-HT) is a biochemical messenger and neurotransmitter synthesized from L-tryptophan. Serotonin has a range of functions, including regulation of gastric motility, and may be related to some psychiatric disorders including schizophrenia and depression. Serotonin is widely distributed in the central and peripheral nervous system, and also in some non-neural tissues such as platelets.
Synonyms	5-HT, 5HT, 5 hydroxytryptamine
Reference Data

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