Rb (RB1) pSer608 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot: 1:500~1:1000. Immunohistochemistry on paraffin sections: 1:50~1:100.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide sequence around phosphorylation site of Serine 608(Y-L-S(p)-P-V) derived from Human Retinoblastoma (KLH-conjugated)
Specificity	The antibody detects endogenous levels of Retinoblastoma only when phosphorylated at serine 608.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity chromatography using epitope-specific peptide
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Predicted Protein Size	110 kDa
Gene Name	RB transcriptional corepressor 1
Database Link	Entrez Gene 5925 Human UniProt ID P06400
Background	Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.
Synonyms	Retinoblastoma 1, Rb, p105-Rb, pRb, pp110, OSRC
Reference Data

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