Claudin-11 / CLDN11 Oligendodendrocyte Rabbit Polyclonal Antibody

CAT#: AP55120SU-N

Claudin-11 / CLDN11 Oligendodendrocyte rabbit polyclonal antibody, Serum



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CNY 6,600.00


货期*
8周

规格
    • 200 ul

Cited in 1 publication.

Product images

Specifications

Product Data
Applications ELISA, IF, IHC, WB
Recommend Dilution ELISA.
Western Blot: 1/200-1/5000.
Immunocytochemistry: 1/400.
Immunohistochemistry: 1/50-1/500.
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Immunogen A 15 residue synthetic peptide derived from C-terminal domain of 22 kDa Claudin-11
Specificity Reacts with Rat 22 kDa OSP protein derived from CNS samples
Formulation State: Serum
State: Lyophilized serum
Preservative: None
Reconstitution Method Restore in 0.2 ml distilled water.
Conjugation Unconjugated
Storage Condition

Prior to reconstitution store the antibody at -20°C.
Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer
Avoid repeated freezing and thawing.

Background Oligodendrocyte specific protein belongs is a major component of central nervous system myelin that is necessary for normal CNS function. The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, and are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that the Claudin 11 protein determines the permeability between layers of myelin sheaths via focal adhesion and with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.
Synonyms OSP, OTM
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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