Diffuse panbronchiolitis critical region protein 1 (DPCR1) (pan) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot: 1/500-1/2000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from Human N-terminal region of Diffuse Panbronchiolitis Critical Region protein 1 (DPCR1)
Specificity	Reacts with 38 kDa DPCR1 protein.
Formulation	State: Serum State: Lyophilized serum Preservative: None
Reconstitution Method	Restore in 0.2 ml distilled water.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	diffuse panbronchiolitis critical region 1
Database Link	Entrez Gene 135656 Human UniProt ID Q3MIW9
Background	DPCR1 (diffuse panbronchiolitis critical region 1), also known as PBLT, is a 517 amino acid single-pass type I membrane protein that exists as 2 alternatively spliced isoforms. Expressed in adult small intestine, uterus, esophagus, lung, kidney, testis, rectum, stomach, cervix and skin, DPCR1 has also been observed in fetal kidney, lung and heart. The gene encoding DPCR1 maps to a region on chromosome 6 that is shared by seven other genes, which have been linked to diffuse panbronchiolitis. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Synonyms	C6orf37, PBLT
Reference Data

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