DcR3 (TNFRSF6B) (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1:1;000. Western blot: 1:100~500. Immunohistochemistry on paraffin sections: 1:50~100.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human TNFRSF6B
Specificity	This antibody detects TNFRSF6B / DCR3 (N-term).
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	tumor necrosis factor receptor superfamily member 6b
Database Link	Entrez Gene 8771 Human UniProt ID O95407
Background	This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.
Synonyms	Decoy receptor 3
Note	Molecular Weight: 32680 Da
Reference Data
Protein Families	Secreted Protein
Protein Pathways	Cytokine-cytokine receptor interaction

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