NCOA1 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1/50-1/100. Enzyme immunoassay: 1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the central region (between 593-625aa) of human NCOA1 / SRC1.
Specificity	This antibody recognizes NCOA1/SRC1.
Formulation	PBS with 0.09% (W/V) Sodium azide State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	nuclear receptor coactivator 1
Database Link	Entrez Gene 8648 Human UniProt ID Q15788
Background	The protein encoded by the NCOA1 gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms	NCoA-1, Nuclear receptor coactivator 1, Steroid receptor coactivator 1, SRC-1, RIP160, Protein Hin-2, NY-REN-52, BHLHE74
Note	Molecular Weight: 156757 Da
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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