SPG7 (Center) Rabbit Polyclonal Antibody
CAT#: AP54017PU-N
SPG7 (Center) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Cited in 1 publication. |
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | Immunohistochemistry on Paraffin Sections: 1/10-1/50. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide - KLH conjugated corresponding to the central region (between 115-141aa) of Human Paraplegin / SPG7 |
Specificity | This antibody recognizes Human Paraplegin / SPG7. Other species not tested. |
Formulation | PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Purified through a Protein A column followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Predicted Protein Size | 88235 Da (calculated) |
Gene Name | SPG7, paraplegin matrix AAA peptidase subunit |
Database Link | |
Background | The SPG7 gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. |
Synonyms | Spastic paraplegia 7 protein, CAR, CMAR, PGN |
Reference Data | |
Protein Families | Protease, Transmembrane |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Abnormal Paraplegin Expression in Swollen Neurites, Ä- and α-Synuclein Pathology in a Case of Hereditary Spastic Paraplegia SPG7 with an Ala510Val Mutation
,Thal DR, ZC |
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