OATP2 (SLCO1B1) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 273~302 amino acids from the Central region of Human SLCO1B1
Specificity	This antibody recognizes Human SLCO1B1 (Center).
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	solute carrier organic anion transporter family member 1B1
Database Link	Entrez Gene 10599 Human UniProt ID Q9Y6L6
Background	SLCO1B1 is a liver-specific member of the organic anion transporter family. This protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
Synonyms	LST1, LST-1, OATP-2, OATPC, OATP-C, SLC21A6
Note	Molecular Weight: 76449 Da
Reference Data
Protein Families	Druggable Genome, Transmembrane

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