Trypsin (PRSS3) (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	Flow cytometry: 1/10-1/50. Immunohistochemistry on Paraffin sections: 1/50-1/100. Western blot: 1/100-1/500. Enzyme immunoassay: 1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 20-48aa) of human Trypsin-3 / PRSS3
Specificity	This antibody recognizes Trypsin-3 / PRSS3.
Formulation	PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Purified through a Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	protease, serine 3
Database Link	Entrez Gene 5646 Human UniProt ID P35030
Background	The PRSS3 gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. PRSS3 is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.
Synonyms	PRSS4, TRY3, TRY4, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV
Note	Molecular Weight: 32529 Da
Reference Data
Protein Families	Druggable Genome, Protease, Secreted Protein
Protein Pathways	Neuroactive ligand-receptor interaction

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