PCDHGC3 (Center) Rabbit Polyclonal Antibody
CAT#: AP53216PU-N
PCDHGC3 (Center) rabbit polyclonal antibody, Aff - Purified
Need it in bulk or conjugated?
Get a free quote
CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | FC, IHC, WB |
Recommend Dilution | Flow Cytometry: 1/10-1/50. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 511-539 amino acids from the to the central region of human PCDHGC3. |
Specificity | This antibody recognizes Human PCDHGC3. Other species not tested. Cellular Location: Cell membrane; Single-pass type I membrane protein. |
Formulation | PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Purified through a Protein A column followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Gene Name | protocadherin gamma subfamily C, 3 |
Database Link | |
Background | The PCDHGC3 gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. |
Synonyms | Protocadherin gamma-C3, PCDH-gamma-C3, Protocadherin-2, Protocadherin 2, PCDH2, Protocadherin-43, Protocadherin 43, PC-43, PC43 |
Note | Molecular Weight: 101077 Da |
Reference Data | |
Protein Families | Transmembrane |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
其它PCDHGC3产品
Customer
Reviews
Loading...