PCBD1 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100. Flow Cytometry: 1/10 - 1/50.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 27~56 amino acids from the Center region of human PCBD1
Specificity	This antibody reacts to PCBD1.
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	12000 Da
Gene Name	pterin-4 alpha-carbinolamine dehydratase 1
Database Link	Entrez Gene 13180 MouseEntrez Gene 5092 Human UniProt ID P61457
Background	PCBD1 encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).
Synonyms	DCOH, PCBD, PHS, Pterin carbinolamine dehydratase
Reference Data
Protein Families	Druggable Genome

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