KAT2B (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/50 - 1/100.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 802-832 amino acids from the C-terminal region of human PCAF
Specificity	This antibody reacts to PCAF.
Formulation	PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	93013 Da
Gene Name	lysine acetyltransferase 2B
Database Link	Entrez Gene 8850 Human UniProt ID Q92831
Background	CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
Synonyms	Histone acetylase PCAF, P/CAF
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Notch signaling pathway

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