NUDT2 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1/100-1/500. Enzyme immunoassay: 1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the central region between 61-90aa) of human NUDT2 /APAH1.
Specificity	This antibody recognizes NUDT2 / APAH1.
Formulation	PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Purified through a Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Gene Name	nudix hydrolase 2
Database Link	Entrez Gene 318 Human UniProt ID P50583
Background	The NUDT2 gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.
Synonyms	Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nudix motif 2
Note	Molecular Weight: 16829 Da
Reference Data
Protein Pathways	Purine metabolism, Pyrimidine metabolism

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