S2P (MBTPS2) (N-term) Rabbit Polyclonal Antibody
CAT#: AP52627PU-N
S2P (MBTPS2) (N-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | ELISA: 1/1000. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human MBTPS2 |
Specificity | This antibody recognizes Human MBTPS2 (N-term). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Gene Name | membrane bound transcription factor peptidase, site 2 |
Database Link | |
Background | This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response. |
Synonyms | Site-2 protease, S2P endopeptidas, S2P |
Note | Molecular Weight: 57444 Da |
Reference Data | |
Protein Families | Druggable Genome, Protease, Transmembrane |
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