MAF1 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	ELISA: 1/1000.  Western Blot: 1/100-1/500. Flow Cytometry: 1/10-1/50.  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 97-125 amino acids from the Central region of human MAF1
Specificity	This antibody recognizes Human and Mouse MAF1 (Center).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	MAF1 homolog, negative regulator of RNA polymerase III
Database Link	Entrez Gene 84232 Human UniProt ID Q9H063
Background	This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression.
Synonyms	Repressor of RNA polymerase III transcription MAF1 homolog
Note	Molecular Weight: 28771 Da
Reference Data
Protein Families	Transcription Factors

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