LRSAM1 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western Blot: 1/1000. Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LRSAM1
Specificity	This antibody recognizes Human and Mouse LRSAM1 (N-term). Cellular Location: Cytoplasm. Note - Displays a punctuate distribution and localizes to a submembranal ring. Tissue Location: Highly expressed in adult spinal cord motoneurons as well as in fetal spinal cord and muscle tissue.
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	leucine rich repeat and sterile alpha motif containing 1
Database Link	Entrez Gene 90678 Human UniProt ID Q6UWE0
Background	LRSAM1 is a multifunctional RING finger protein that selectively regulates cell adhesion molecules, has ubiquitin ligase activity, and plays a role in receptor endocytosis and viral budding (Li et al., 2003 [PubMed 14635195]; Amit et al., 2004 [PubMed 15256501]).
Synonyms	Tsg101-associated ligase, TAL
Note	Molecular Weight: 83594 Da
Reference Data
Protein Families	Druggable Genome

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