IREB2 (Center) Rabbit Polyclonal Antibody

CAT#: AP52232PU-N

IREB2 (Center) rabbit polyclonal antibody, Aff - Purified



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CNY 6,160.00


货期*
5周

规格
    • 400 ul

Product images

Specifications

Product Data
Applications FC, IHC, WB
Recommend Dilution ELISA: 1/1000.
Western Blot: 1/100-1/500.
Flow Cytometry: 1/10-1/50.
Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human IREB2
Specificity This antibody recognizes Human IREB2 (201-230).
Formulation PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein A column, followed by peptide affinity purification
Conjugation Unconjugated
Storage Condition

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Gene Name iron responsive element binding protein 2
Background IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3' UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Synonyms IRE-BP2, Iron regulatory protein 2, IRP2
Note Molecular Weight: 105045 Da
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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