HOXD10 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: 1/500 - 1/1000.
Reactivity	Human, Mouse, Zebrafish
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 305-334 amino acids from the C-terminal region of Human HOXD10
Specificity	This antibody recognizes Mouse and Zebrafish HOXB10 (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	homeobox D10
Database Link	Entrez Gene 15430 MouseEntrez Gene 3236 Human UniProt ID P28358
Background	This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
Synonyms	Homeobox protein Hox-D10, HOX4D, Hox-4D, Hox-4E
Note	Molecular Weight: 38411 Da
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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