GBE1 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ELISA:  1/1000.  Western Blot: 1/100-1/500.  Immunofluorescence: 1/10-1/50.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 534~564 amino acids from the Central region of human GBE1
Specificity	This antibody recognizes Human and Mouse GBE1 (Center).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	glucan (1,4-alpha-), branching enzyme 1
Database Link	Entrez Gene 2632 Human UniProt ID Q04446
Background	GBE1 is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease.
Synonyms	Glycogen-branching enzyme, Brancher enzyme
Note	Molecular Weight: 80460 Da
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Starch and sucrose metabolism

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