FRAT2 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500.  Immunofluorescence: 1/10-1/50.  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 210-233 amino acids from the C-terminal region of human FRAT2
Specificity	This antibody recognizes Human FRAT2 (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	frequently rearranged in advanced T-cell lymphomas 2
Database Link	Entrez Gene 23401 Human UniProt ID O75474
Background	The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.
Synonyms	GSK-3-binding protein Frat-2
Note	Molecular Weight: 24051 Da
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS
Protein Pathways	Wnt signaling pathway

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