FGD4 (N-term) Rabbit Polyclonal Antibody
CAT#: AP51651PU-N
FGD4 (N-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | ELISA: 1/1000. Western Blot: 1/100 - 1/500. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 156-186 amino acids from the N-terminal region of human FGD4 |
Specificity | This antibody reacts to FGD4. |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Predicted Protein Size | 86626 Da |
Gene Name | FYVE, RhoGEF and PH domain containing 4 |
Database Link | |
Background | This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq]. |
Synonyms | FRABP, ZFYVE6, Frabin |
Reference Data |
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