DEK (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IHC, WB
Recommend Dilution	ELISA: 1/1000. Western blot: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100. Flow Cytometry: 1/10 - 1/50. Immunofluorescence: 1/10 - 1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 343~372 amino acids from the C-terminal region of human DEK
Specificity	This antibody reacts to DEK.
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	42674 Da
Gene Name	DEK proto-oncogene
Database Link	Entrez Gene 7913 Human UniProt ID P35659
Background	DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases.
Synonyms	Protein DEK
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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