bcl 6 (BCL6) (C-term) Rabbit Polyclonal Antibody
CAT#: AP50359PU-N
bcl 6 (BCL6) (C-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | ELISA: 1/1000. Western blotting: 1/100 - 1/500. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 675-704 amino acids from the C-terminal region of human BCL6 |
Specificity | This antibody reacts to Bcl-6. |
Formulation | PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | B-cell CLL/lymphoma 6 |
Database Link | |
Background | The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. |
Synonyms | BCL6, BCL5, BCL-5, LAZ3, LAZ-3, ZBTB27, ZNF51 |
Note | Molecular Weight: 78846 Da |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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