AP2M1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, WB
Recommend Dilution	ELISA: 1/1000. Western blotting: 1/100-1/500. Flow Cytometry: 1/10-1/50
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of Human AP2M1
Specificity	This antibody recognizes AP2 complex subunit mu-1.
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	49655 Da
Gene Name	adaptor related protein complex 2 mu 1 subunit
Database Link	Entrez Gene 11773 MouseEntrez Gene 1173 Human UniProt ID Q96CW1
Background	This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms	CLAPM1, KIAA0109, Adaptin-mu2, AP-2 mu-2 chain
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Endocytosis, Huntington's disease

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