AASS (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, WB
Recommend Dilution	ELISA: 1/1000. Western blotting: 1/50 - 1/100. Flow Cytometry: 1/10 - 1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 812-841 amino acids from the C-terminal region of human AASS.
Specificity	This antibody reacts to AASS.
Formulation	PBS with 0.09% (W/V) sodium azide as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	aminoadipate-semialdehyde synthase
Database Link	Entrez Gene 10157 Human UniProt ID Q9UDR5
Background	This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
Synonyms	LKR/SDH
Note	Molecular Weight: 102132 Da
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Lysine biosynthesis, Lysine degradation, Metabolic pathways

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