Aminoadipate aminotransferase (AADAT) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELIS: 1/1000. Western blotting: 1/100 - 1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 203-232 amino acids from the Central region of human AADAT
Specificity	This antibody reacts to AADAT.
Formulation	PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	aminoadipate aminotransferase
Database Link	Entrez Gene 51166 Human UniProt ID Q8N5Z0
Background	This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.
Synonyms	KAT2, Kynurenine aminotransferase II, Kynurenine-oxoglutarate aminotransferase II, Kynurenine-oxoglutarate transaminase II, 2-aminoadipate transaminase, 2-aminoadipate aminotransferase, Alpha-aminoadipate aminotransferase
Note	Molecular Weight: 47352 Da
Reference Data
Protein Pathways	Lysine biosynthesis, Lysine degradation, Metabolic pathways, Tryptophan metabolism

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