MAPT / TAU Chicken Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western blotting: 1/10,000. Immunohistochemistry. Immunofluorescence: 1/1000.
Reactivity	Human, Rat
Host	Chicken
Clonality	Polyclonal
Immunogen	Recombinant full length Human Tau expressed in and purified from E. coli.
Specificity	Specific for the ~48, 65 & 75kDa Tau isoforms.
Formulation	State: Ig Fraction State: Liquid Total IgY fraction Preservative: 10 mM Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	microtubule associated protein tau
Database Link	Entrez Gene 4137 Human UniProt ID P10636
Background	Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy.
Synonyms	MAPTL, MTBT1, Microtubule-associated protein tau, PHF-tau, Neurofibrillary tangle protein, Paired helical filament-tau
Reference Data

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