HIST4H4 (acetyl K5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA: 1/1000. Immunofluorescence: 1/100 - 1/500. Immunohistochemistry on Paraffin Sections: 1/200. Western Blot: 1/500 - 1/1000.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide from Human Histone H4 around the acetylated site of Lys5.
Specificity	This antibody detects endogenous levels of total Histone H4 protein only when acetylated at Lysine5.
Formulation	PBS (without Mg2+, Ca2+), pH 7.4 containig 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	histone cluster 4, H4
Database Link	Entrez Gene 554313 HumanEntrez Gene 121504 Human UniProt ID P62805
Background	Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones.
Synonyms	HIST1H4, H4/A, H4FA
Reference Data
Protein Pathways	Systemic lupus erythematosus

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