Thyroid Peroxidase (TPO) (C-term) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	Peptide ELISA: 1/32000 (Detection Limit). Western blot: 0.1-0.3 µg/ml. Approx 110kDa band observed in Human Thyroid Gland lysates (calculated MW of 103kDa according to NP_000538.3). Immunohistochemistry on Paraffin Sections: 5-10 µg/ml. In paraffin embedded Human Thyroid Gland shows textured staining in the cytoplasm of epithelial cells.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence from the C Terminus of the protein sequence according to NP_000538.3; NP_783650.1; NP_783652.1; NP_783653.1.
Specificity	This antibody is expected to recognize all reported isoforms of Thyroid Peroxidase (NP_000538.3; NP_783650.1; NP_783652.1; NP_783653.1).
Formulation	Tris saline, pH~7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	thyroid peroxidase
Database Link	Entrez Gene 7173 Human UniProt ID P07202
Background	Thyroid peroxidase (TPO) is an enzyme expressed in the thyroid gland which is necessary for the production of thyroid hormes such as thyroxine. Congenital hypothyroidism and congenital goiter are both associated with mutations in the TPO gene.
Synonyms	MSA; OTTHUMP00000115536; TDH2A; thyroperoxidase; TPX
Reference Data

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