MUSK pTyr755 Rabbit Polyclonal Antibody

CAT#: AP26453PU-S

MUSK pTyr755 rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul



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CNY 1,400.00


货期*
2周

规格
    • 50 ul

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Specifications

Product Data
Applications WB
Recommend Dilution Western blot.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of tyrosine 755(A-D-Y(p)-Y-K) derived from Human MuSK (KLH-conjugated)
Specificity The antibody detects endogenous levels of MuSK only when phosphorylated at tyrosine 755.
Formulation Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity-chromatography using epitope-specific phosphopeptide
Conjugation Unconjugated
Storage Condition Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Predicted Protein Size 97 kDa
Gene Name muscle associated receptor tyrosine kinase
Background
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between
the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of
MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes
including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine
receptors (AChR) in the postsynaptic membrane.
Synonyms Muscle-specific kinase receptor
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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